What are Peptides for Weight Loss?

Peptides Weight Loss

Peptides are chains of amino acids. Many people use peptides for weight loss because peptides have some amazing benefits. Peptides can regulate your appetite, increase metabolism, improve muscle gain and burn fat! Let’s find out the best peptides for weight loss.

How peptides help in weight loss

Different peptides have different functions in our body. Peptides work in the following ways

  1. Increase metabolic rate – we burn more calories
  2. Increase GH stimulation – more fat burning
  3. Reduce appetite and food intake – your feel less hungry
  4. Stimulate IGF-1 production – improves muscle gain

Best peptides for weight loss


Semaglutide is a GLP-1 receptor agonist. Glucagon Like Peptide 1 is a natural hormone in the body. Semaglutide regulates blood sugar levels, increases the level of insulin and reduces glucagon levels. 

The end result is that we feel a reduced appetite and we eat fewer calories and this helps in weight loss. There is ample research done on this peptide and it has been shown effective for weight loss.


This drug is approved by the FDA for chronic weight management. It helps with people with type 2 diabetes, high cholesterol and high blood pressure. This peptide works in a dual manner. It targets the GLP-1 receptors, this helps in regulating the appetite.

It also targets the GIP (glucose dependent insulinotropic receptors), which helps with appetite regulation and fat storage. Reseras show that it helps you with up to 20% weight loss in 6 months.


Tesamorelin is a GHRH or growth hormone releasing hormone. It works by stimulating the release of growth hormone from the pituitary. The growth hormone helps in reducing body fat.

Some of the side-effects of Tesamorelin are joint pain, stiffness, or mild numbness.


Sermorelin is a GHRH peptide. It consists of 29 amino acids. Sermorelin boosts GH Production. Which in turn stimulates the liver to produce IGF-1. Sermorelin can be used for anti-aging and muscle growth as well. It also boosts metabolism and helps with fat loss. 

Sermorelin is an FDA approved drug and can be obtained with a doctor’s prescription. It can have mild side effects like headache, dizziness, nausea. 

CJC 1295

CJC 1295 is a GHRH. It works by stimulating Growth hormone release from the pituitary. It has a high bioavailability and short half life of 30 mins.

CJC 1295 can be used for muscle gain, fat loss and recovery. Common side effects are headache, dizziness.


AOD-9604 is a peptide obtained from HGH or human growth hormone. It contains an amino acid chain 176-191. It is lipolytic in nature, Once injected it increases the beta-3 adrenergic receptor activity.  It stimulates fat loss by burning fatty acids in the body.  Along with fat loss it is also used for bone or joint damage. It is approved by the FDA to use. Common side effects are redness, swelling at the injection site.


PYY or Peptide YY is a 36 amino acid chain. It is naturally secreted by the presence of food in the digestive tract. PYY does not have a direct effect on fat loss but it reduces your appetite and increases satiety level, thus making you eat less food. It is approved by the FDA, it is considered generally safe but it can have some side effects like nausea or diarrhea.

Side effects of peptides for weight loss

Each peptide has a different function, mechanism of action and different side effects. However, common side effects are nausea, headache, and dizziness. Some peptides may also cause Nausea, constipation. Some peptides may cause low blood sugar, redness or swelling at the injection side.

Benefits of peptides for weight loss

Peptides have several benefits for fat loss

  1. Increased fat burning – Peptides stimulate GH release which aids in fat burning.
  2. Increased IGF-1 levels – this leads increased muscle gain
  3. Increased metabolism – peptides are know to increase metabolism thus higher calorie burn and weight loss
  4. Improved immune functions and recovery
  5. Improved health of joints and bones

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